GJB1 Mouse Monoclonal Antibody [Clone ID: CXN-32]

Specifications

Product Data
Clone Name	CXN-32
Applications	IHC, WB
Recommend Dilution	Western Blot: 0.5 - 1 μg/ml. Immunohistochemistry on frozen sections: 1 - 2 μg/ml.
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic connexin-32 peptide (amino acids 105-123) conjugated to KLH.
Specificity	This antibody reacts to GJB1 / Cx32.
Formulation	1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative. State: Purified State: Lyphilized purified Ig fraction
Reconstitution Method	Restore with 1.2% sodium acetate or neutral PBS
Concentration	0,1 mg/ml (after reconstitution with PBS)
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at -20°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	gap junction protein beta 1
Database Link	Entrez Gene 14618 MouseEntrez Gene 29584 RatEntrez Gene 2705 Human UniProt ID P08034
Background	Connexin32(CX32), also known as GAP junction protein beta-1(GJB1). Connexins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. CX32 expressed in liver and peripheral nerve. CX32 gene is mapped to Xp11-q13 and is directly regulated by the transcription factor SOX10.
Synonyms	Gap junction beta-1 protein, Connexin-32
Reference Data
Protein Families	Druggable Genome, Ion Channels: Other, Transmembrane

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