hCG beta (CGB3) Mouse Monoclonal Antibody [Clone ID: HCG-8]

Specifications

Product Data
Clone Name	HCG-8
Applications	IHC
Recommend Dilution	Immunohistochemistry on Paraffin Sections: Use at 0.25-0.5 μg/ml to detect beta-HCG in Formalin Fixed and Paraffin Embedded Tissues.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified Human Chorionic Gonadotropin.
Specificity	Recognizes Human Chorionic gonadotropin (beta-subunit) and does not cross reacts with other Proteins (hLH, hTSH, or hFSH).
Formulation	1.2% Sodium Acetate containing 2 mg BSA and 0.01 mg Sodium Azide as preservative State: Purified State: Lyophilized purified IgG fraction
Reconstitution Method	Restore with 1.2% Sodium Acetate or neutral PBS.
Concentration	0.1 mg/ml (after reconstitution with 1 ml PBS).
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store the antibody after reconstitution at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	chorionic gonadotropin beta subunit 3
Database Link	Entrez Gene 1082 Human UniProt ID P0DN86
Background	HCG beta (beta-Human Chorionic Gonadotropin), also termed as Chorionic Gonadotropin, Beta Chain (CGB).It is encoded by a multigene cluster composed of six homologous sequences. And in the family of beta-containing glycoprotein hormones, β-HCG is unique in that it contains an extension of 29 amino acids at its COOH end. HCG beta is mapped to 19q13.32 and expressed in trophoblast and various malignant tumors promotes cellular motility in vivo. Beta-HCG has a novel function in uterine adaptation to early pregnancy as well as in tumor development and underline the importance of HCG as an as yet unrecognized angiogenic factor.
Synonyms	Choriogonadotropin subunit beta, CGB, CGB3, beta hCG, hCG-beta
Reference Data
Protein Families	Druggable Genome

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