Involucrin (IVL) Mouse Monoclonal Antibody [Clone ID: IL-9]

Specifications

Product Data
Clone Name	IL-9
Applications	IF, IHC, IP, WB
Recommend Dilution	Western Blot: 2 μg/ml. Immunohistochemistry on paraffin and frozen sections: 0.4 - 1 μg/ml. Immunocytochemical.
Reactivity	Canine, Human, Porcine
Host	Mouse
Clonality	Monoclonal
Immunogen	Human involucrin
Specificity	This antibody reacts to Involucrin.
Formulation	1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative. State: Purified State: Lyphilized purified Ig fraction
Reconstitution Method	Restore with 1.2% sodium acetate or neutral PBS
Concentration	0,1 mg/ml (after reconstitution with PBS)
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at -20°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	involucrin
Database Link	Entrez Gene 3713 Human UniProt ID P07476
Background	Involucrin is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. The gene consists of 585 amino acids, 390 of which form a central decapeptide repeat, rich in glutamine and glutamic acid. The involucrin gene,encoding a protein of the terminally differentiated keratinocyte, is polymorphic in the human. Involucrin has previously been mapped to chromosome 1q21. The epidermal protein involucrin has been remodeled in the higher primates. And the existence of two populations of East Asian involucrin alleles gives support for the existence of a Eurasian stem lineage from which Caucasians and a part of the Asian population originated.
Synonyms	involucrin
Reference Data

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