CD36 Mouse Monoclonal Antibody [Clone ID: CB38 (NL07)]

Specifications

Product Data
Clone Name	CB38 (NL07)
Applications	FC
Recommend Dilution	Flow Cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 10e6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Living human myeloid cells
Specificity	The mouse monoclonal antibody CB38 (NL07) recognizes CD36 (GPIIIb), a 85-113 kDa integral membrane glycoprotein expressed on platelets, macrophages, endothelial cells, early erythroid cells and megakaryocytes.
Formulation	PBS Label: PE State: Liquid Ig fraction Stabilizer: 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) Preservative: 15 mM sodium azide
Purification	Size-exclusion chromatography
Conjugation	PE
Storage Condition	Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Gene Name	CD36 molecule
Database Link	Entrez Gene 948 Human UniProt ID P16671
Background	CD36 (fatty acid translocase, FAT) is an 85-113 kDa ditopic glycosylated protein that belongs to the class B family of scavenger receptors. CD36 is expressed by most resting marginal zone B cells but not by follicular and B1 B cells, and it is rapidly induced on Follicular B cells in vitro upon TLR and CD40 stimulation. CD36 does not affect the development of B cells, but modulates both primary and secondary antibody response. Similarly to glucose transporter GLUT4, CD36 is translocated from intracellular pools to the plasma membrane following cell stimulation by insulin. In mouse, CD36 is responsible for gustatory perception of long-chain fatty acids.
Synonyms	Glycoprotein IIIb, PAS IV, PAS-4, Thrombospondin receptor, GP3B, GP4
Reference Data

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