AGR3 Mouse Monoclonal Antibody [Clone ID: AGR3.1]

Specifications

Product Data
Clone Name	AGR3.1
Applications	FC, IF, IHC, WB
Recommend Dilution	Western blot: 1 μg/ml. Positive Control: T47D breast cancer cell line. Negative Control: H1299 lung carcinoma cell line. Immunohistochemistry on Paraffin Sections: 1 μg/ml. Positive Tissue: breast cancer. Immunohistochemistry on Frozen Sections: 1 μg/ml. Positive Tissue: breast cancer. Immunocytochemistry: 1 μg/ml. Positive Control: T47D breast cancer cell line. Negative Control: H1299 lung carcinoma cell line.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified Human AGR3 protein.
Specificity	This antibody recognizes the epitope HETTDKNLS within the AGR3 (AG3) protein (19-20 kDa), a secreted cytoplasmic protein which can serve as a marker of carcinogenesis.
Formulation	PBS State: Aff - Purified State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE) Stabilizer: 0.2% (w/v) high-grade protease free BSA Preservative: 15 mM Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	anterior gradient 3, protein disulphide isomerase family member
Database Link	Entrez Gene 155465 Human UniProt ID Q8TD06
Background	AGR3 (Anterior Gradient 3) protein, also known as AG3 (hAG-3, HAG3 in human), or BCMP11, is a secreted cytoplasmic protein which is involved in metastasis induction and p53 tumour supressor inhibition. It may serve as molecular marker and potential therapeutic target for hormone-responsive breast tumours. Its Xenopus homolog is associated with anteroposterior fate determination during early development.
Synonyms	BCMP11, HAG3, HAG-3
Reference Data

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