TAPA1 (CD81) Mouse Monoclonal Antibody [Clone ID: M38]

Specifications

Product Data
Clone Name	M38
Applications	FC
Recommend Dilution	Flow Cytometry analysis of human blood cells using 20 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
Reactivity	Feline, Human, Rabbit
Host	Mouse
Clonality	Monoclonal
Immunogen	MOLT-4 (human T-ALL cell line)
Specificity	This antibody reacts with CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.
Formulation	Phosphate buffered saline (PBS) solution containing 15mM sodium azide Label: FITC State: Liquid purified Ig fraction Label: Conjugated with Fluorescein isothiocyanate under optimum conditions. The reagent is free of unconjugated and adjusted for direct use. No reconstitution is necessary.
Conjugation	FITC
Storage Condition	Store the antibody at 2-8°C. Do Not Freeze! This product is photosensitive and should be protected from light.
Gene Name	CD81 molecule
Database Link	Entrez Gene 975 Human UniProt ID P60033
Background	CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells – e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.
Synonyms	S5.7; TAPA-1; TAPA1; Tetraspanin-28; Tspan-28; TSPAN28
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways	B cell receptor signaling pathway

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