Cr1l Mouse Monoclonal Antibody [Clone ID: 512]

Specifications

Product Data
Clone Name	512
Applications	FC, IHC
Recommend Dilution	Immunohistochemistry on frozen sections: 0.1 μg/ml (1:4000). Does not react on routinely processed paraffin sections. Has been reported to work in FACS. Suggested positive control: rat spleen.
Reactivity	Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Erythrocytes from a C3 mutated rat
Specificity	This antibody detects Crry. The antigen is found on numerous cells in blood and various tissues.
Formulation	Stock solution contains 0.4 mg/ml IgG, phosphate buffered saline pH 7.2 (PBS), 5mg/ml bovine serum albumin (BSA) as a stabilizer and 0.09% sodium azide as a preservative. State: Aff - Purified State: Liquiphilized Ig fraction
Reconstitution Method	Reconstitute by adding 0.5 ml distilled water.
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at 2-8°C. Following reconstitution store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	complement component (3b/4b) receptor 1-like
Database Link	Entrez Gene 54243 Rat UniProt ID Q63135
Background	Crry is a cofactor for complement factor I. Crry seems to act as a costimulatory factor for T-cells and is expressed on different tissues, particularly also on thymocytes and non-lymphoid cells in the thymus. Crry may play an important role in the early embryonic development by maintaining fetomaternal tolerance. Two forms of Crry exist, containing six or seven extracellular short consensus repeats (SCRs), respectively, plus a transmembrane and a cytoplasmic domain. The molecular weights of the native glycoproteins are approximately 55 and 65kDa, respectively.
Synonyms	Antigen 5I2
Reference Data

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