Laminin alpha 5 (LAMA5) Mouse Monoclonal Antibody [Clone ID: 4B12]

Specifications

Product Data
Clone Name	4B12
Applications	ELISA, IF, IHC, IP
Recommend Dilution	ELISA: 1/8000. Immunoprecipitation: 1/20. Immunohistochemistry: 1/100–1/200. This antibody does Not work in Western blot!
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Laminin purified from Human placenta (Chemicon)
Specificity	This antibody detects Laminin alpha 5.
Formulation	PBS, pH 7.4 State: Purified State: Liquid purified Ig fraction Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatorgaphy on Protein G
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	laminin subunit alpha 5
Database Link	Entrez Gene 3911 Human UniProt ID O15230
Background	Laminins are a family of large heterotrimeric proteins that promote cell adhesion and migration via integrins and other cellsurface receptors. They are major components of basement membranes of blood vessels and other tissue compartments, and are synthesized by numerous cell types. Through combination, laminin chains constitute 15 laminin isoforms. Laminin isoforms, particularly their > chain, are expressed in a cell- and tissue-specific manner, and are differentially recognized by integrins.
Synonyms	LAMA5, KIAA0533, KIAA1907, Laminin subunit alpha-5
Reference Data
Protein Families	Druggable Genome
Protein Pathways	ECM-receptor interaction, Focal adhesion, Pathways in cancer, Small cell lung cancer

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