LTF (C-lobe) Mouse Monoclonal Antibody [Clone ID: a-bC-lobe]

Specifications

Product Data
Clone Name	a-bC-lobe
Applications	ELISA, WB
Recommend Dilution	Western blot. Immunoassay (detection). The typical starting working dilution is 1:10.
Reactivity	Bovine, Goat, Human
Host	Mouse
Clonality	Monoclonal
Specificity	This antibody shows strong reactivities with both native and denatured forms of bovine lactoferrin and C-lobe. The 'WNIPMGL' sequence (467-473 of bovine lactoferrin) is the antigenic determinant or epitopic site of the anti C-lobe antibody a-bC-lobe. The antibody shows weak reactivity with human lactoferrin and korean goat lactoferrin, slight cross reactivity is seen with bovine transferrin, whereas no cross reactivity is seen with human transferrin and chicken ovotransferrin.
Formulation	PBS State: Purified State: Liquid 0.2 µm filtered Ig fraction Stabilizer: 0.1% bovine serum albumin Preservative: 0.02% sodium azide
Concentration	lot specific
Purification	Protein G purified
Conjugation	Unconjugated
Storage Condition	Store at 2 - 8 °C.
Database Link	Entrez Gene 280846 Bovine UniProt ID P24627
Background	Lactoferrin is a member of the transferrin family of metal-binding proteins found in milk and other secretory fluids and also in blood. It shows multifunctional properties of which the bacteriostatic and bactericidal effects are the best known. The molecule is constructed with a N-terminal half molecule (N-lobe) and a C-terminal half molecule (C-lobe), each of which is composed of two domains. The biologically important functions have been found mainly in the N-lobe. The lactoferrin determinants responsible for binding to Ca2+-dependent receptor on hepatocytes are present within the C-lobe.
Synonyms	LTF, LF, Lactoferrin, EC=3.4.21, Talalactoferrin
Reference Data

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