FABP3 Mouse Monoclonal Antibody [Clone ID: 66E2]

Specifications

Product Data
Clone Name	66E2
Applications	ELISA, IP, WB
Recommend Dilution	Immunoassay. Immunoprecipitation: Biotinylated 66E2 was immobilized on streptavidin beads and added to serum to immunoprecipitate H-FABP (Ref.5). Western blot: Reduced sample treatment. The band size is ~15 kDa (Ref.4): The typical starting working dilution is 1:50. Positive control: Heart cells, or recombinant H-FABP.
Reactivity	Human, Mouse, Porcine, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified Human H-FABP
Specificity	The monoclonal antibody 66E2 recognizes human heart-type fatty acid-binding protein (H-FABP) of both natural and recombinant origin. It is also useful as marker for brain damage. Furthermore, this antibody is useful for the purification of H-FABP. Shows average cross reactivity on Human B-FABP in ELISA. Deos not bind to Human A-FABP, Human I-FABP, or Human L-FABP.
Formulation	PBS State: Purified State: Liquid 0.2 µm filtered Ig fraction Stabilizer: 0.1% bovine serum albumin Preservative: 0.02% sodium azide
Concentration	lot specific
Purification	Protein G
Conjugation	Unconjugated
Storage Condition	Store at 2 - 8 °C.
Gene Name	fatty acid binding protein 3
Database Link	Entrez Gene 2170 Human UniProt ID P05413
Background	The H-FABP protein is derived from the human FABP3 gene. FABPs are small intracellular proteins (~13-14 kDa) with a high degree of tissue specificity that bind long chain fatty acids. They are abundantly present in various cell types and play an important role in the intracellular utilization of fatty acids, transport and metabolism. There are at least nine distinct types of FABP, each showing a specific pattern of tissue expression. Due to its small size, FABP leaks rapidly out of ischemically damaged necrotic cells leading to a rise in serum levels. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. H-FABP is localized in the heart, skeletal and smooth muscle, mammary epithelial cells, aorta, distal tubules of the kidney, lung, brain, placenta, and ovary.
Synonyms	FABP11, MDGI, H-FABP, Heart-type fatty acid-binding protein
Reference Data

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