GC1q R (C1QBP) Mouse Monoclonal Antibody [Clone ID: 74.5.2]
CAT#: AM26293PU-N
GC1q R (C1QBP) mouse monoclonal antibody, clone 74.5.2, Purified
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CNY 5,729.00
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Specifications
Product Data | |
Clone Name | 74.5.2 |
Applications | ELISA, FN, IF, IP, WB |
Recommend Dilution | Flow Cytometry: The typical starting working dilution is 1/50. Functional Assays. Immunoassays. Immonofluorescence. Immunoprecipitation. Western blot: The typical starting working dilution is 1/50. |
Reactivity | Human, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Recombinant gC1qR corresponding to mature gC1qR (amino acids 74-282) |
Specificity | The monoclonal antibody 74.5.2 recognizes a cell membrane C1q binding molecule that recognises the globular heads of C1q. It is also present in plasma and the extracellular matrix. It is directed against epitopes in the XC15 peptide that contains a binding site for high-molecular-weight kininogen and Factor XII. Clone 74.5.2 recognizes both the mature (74-282) and truncated form, lacking residues 74-95. |
Formulation | PBS State: Purified State: Liquid 0.2 µm filtered Ig fraction Stabilizer: 0.1% BSA |
Concentration | lot specific |
Purification | Protein G Chromatography |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C. |
Gene Name | complement component 1, q subcomponent binding protein |
Database Link | |
Background | The molecule is an unusually acidic, single chain protein with an apparent molecular weight of 33 kDa. It does not possess a conventional sequence motif compatible with a membrane spanning segment nor a consensus site for a GPI anchor. gC1qR migrates as a single chain under both reducing and non-reducing conditions, but it behaves as an oligomer on gel-filtration in non-dissociating conditions. Its multimer formation may be a critical process by which the gC1qR molecule increases its affinity for multivalent ligands such as C1q. |
Synonyms | GC1QBP, HABP1, SF2P32, GC1q-R protein, p33, p32 |
Reference Data |
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