Interferon gamma (IFNG) Mouse Monoclonal Antibody [Clone ID: F12]

Specifications

Product Data
Clone Name	F12
Applications	ELISA, FN, IHC, IP
Recommend Dilution	Immuno assays. Immunohostochemistry on frozen sections: The typical starting working dilution is 1:10. Immunoprecipitation. Functional assays: Neutralization of the biological activity of Interferon gamma. One neutralizing unit of anti-human gamma interferon is defined as the amount of antibody sufficient for neutralizing one unit human gamma interferon (ref.: NIH standard Gg23-901-530).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Specificity	Monoclonal antibody binds and neutralizes both natural and recombinant human gamma Interferon. Cross reactivity with other cytokines has not been found. Possible applications include the purification of human gamma Interferon and in vitro neutralisation. In general, monoclonal antibodies to gamma Interferon are able to inhibit Schwartzman reactions and in the murine system appear to protect NZB mice against spontaneous development of autoimmune disease.
Formulation	PBS State: Purified State: Lyophilized Ig fraction
Reconstitution Method	Reconstitute by injection of 1 ml distilled or de-ionized water (Caution: vial is under vacuum).
Purification	Protein G
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at 2-8°C. Following reconstitution store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	interferon, gamma
Database Link	Entrez Gene 3458 Human UniProt ID P01579
Synonyms	IFN-gamma, gamma IFN
Reference Data

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