Jam3 Rat Monoclonal Antibody [Clone ID: 19H36]
CAT#: AM26321PU-N
Jam3 rat monoclonal antibody, clone 19H36, Purified
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CNY 5,820.00
货期*
5周
规格
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Specifications
Product Data | |
Clone Name | 19H36 |
Applications | ELISA, IHC, IP |
Recommend Dilution | Immunohistochemistry on frozen sections: The typical starting working dilution is 1:50. Flow cytometry: The typical starting working dilution is 1:50. Immunoassay. Immunoprecipitation. Does not work in Western blot and immunohistology on paraffin sections. |
Reactivity | Human, Mouse |
Host | Rat |
Clonality | Monoclonal |
Specificity | This antibody detects JAM-C. In humans, JAM-C expression is not restricted to endothelial cells, but is also expressed on human lymphocytes. |
Formulation | PBS State: Purified State: Liquid 0.2 µm filtered Ig fraction Stabilizer: 0.1% bovine serum albumin Preservative: 0.02% sodium azide |
Concentration | lot specific |
Purification | Protein G |
Conjugation | Unconjugated |
Storage Condition | Store at 2 - 8 °C. |
Gene Name | junction adhesion molecule 3 |
Database Link | |
Background | Junctional adhesion molecule-C (JAM-C) also known as JAM-2 is a 45 kD cell adhesion molecule (CAM). JAM-C is a transmembrane protein which is a member of the immunoglobulin superfamily found at intercellular junctions of endothelial cells. JAM-C belongs together with JAM-A (JAM or JAM-1) and JAM-B (VE-JAM or JAM-3) to a family of adhesion proteins with a V-C2 immunoglobulin domain organization. JAM plays an important role in tight junctions where it is involved in cell-to-cell adhesion through homophilic interaction. It codistributes with other tight junction components as ZO-1, 7H6 antigen, cingulin and occludin. JAM-C is potentially involved in the junctional sealing of the vascular endothelium, in particular of high endothelial venules (HEV). In adult murine tissue JAM-C expression is reported to be restricted to high endothelial venules of lymphoid organs, lymphoendothelial cells and endothelial cells in kidney. |
Synonyms | FLJ14529; JAM-2; JAM-3; JAM-C; JAMC |
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