Polymyxin B Mouse Monoclonal Antibody [Clone ID: 45]

CAT#: AM26366LE-N

Polymyxin B mouse monoclonal antibody, clone 45, Low Endotoxin



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CNY 7,031.00


货期*
5周

规格
    • 200 ug

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Specifications

Product Data
Clone Name 45
Applications ELISA, WB
Recommend Dilution Immunoassays.
Western blot: The typical starting working dilution is 1/10.
Reactivity Human
Host Mouse
Clonality Monoclonal
Specificity The monoclonal antibody 45 reacts with Polymyxin B. It enables the possibilities to study quantitatively the interaction of PMB and LPS.
Formulation State: Low Endotoxin
State: Liquid Culture Medium with a Low endotoxin Level
Preservative: 0.02% Sodium Azide
Concentration lot specific
Conjugation Unconjugated
Storage Condition

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Background The peptide antibiotic Polymyxin B (PMB) binds to bacterial endotoxin (lipopolysaccharide, LPS). The interaction of PMB with LPS involves ionic forces between amino groups in PMB and negatively charged phosphate and carboxyl groups in the lipid A-Kdo region. PMB has relevance for endotoxin research in at least two ways: first, PMB reacts with LPS of many species regardless of varied serospecificity, and thus it can be used as a general probe for measuring or detecting LPS or lipid A. Second, binding of PMB to LPS may result in neutralization of the detrimental effects of LPS either in vitro or in vivo.
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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