alpha Synuclein (SNCA) (1-140) Mouse Monoclonal Antibody [Clone ID: 8F12]
CAT#: AM26403PU-L
alpha Synuclein (SNCA) (1-140) mouse monoclonal antibody, clone 8F12, Aff - Purified
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CNY 6,120.00
货期*
4周
规格
Specifications
Product Data | |
Clone Name | 8F12 |
Applications | WB |
Recommend Dilution | Western blot. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Recombinant human α-synuclein (1-140 aa) expressed in E. coli |
Specificity | This antibody recognizes the recombinant α-synuclein. |
Formulation | 0.01M PBS pH7.2 State: Aff - Purified State: Lyophilized Ig fraction |
Reconstitution Method | Double distillated water is recommended to adjust the final concentration to 1.00 mg/ml. |
Purification | Protein G affinity purified |
Conjugation | Unconjugated |
Storage Condition | Store at -20 °C. Avoid repeated freezing and thawing. |
Gene Name | synuclein alpha |
Database Link | |
Background | Alpha-Synuclein belongs to a family of small cytoplasmic proteins expressed predominantly in neurons. Alpha-synuclein may be involved in neuronal plasticity and could act as a molecular chaperone that mediates the transformation of soluble Aβ into insoluble amyloid. The protein is a major component of Lewy bodies, the pathological hallmark of Parkinson’s disease, and is also observed in senile plaques of Alzheimer’s disease patients. Human α-synuclein appears to be phosphorylated at two major sites, serine 129 and serine 87, and phosphorylation may play a role in the functional regulation of the protein. |
Synonyms | NACP, PARK1 |
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