HLA Class II DR Monoclonal Antibody [Clone ID: L243]

Specifications

Product Data
Clone Name	L243
Applications	FC, FN, IF, IHC, IP, WB
Recommend Dilution	Flow cytometry. Immunoprecipitation. Western blot. Immunohistochemistry (paraffin sections). Immunohistochemistry (frozen sections). Immunocytochemistry. Functional Application: blocking.
Reactivity	Canine, Human, Primate
Clonality	Monoclonal
Immunogen	Human B lymphocytes
Specificity	This antibody recognizes specifically HLA-DR molecules, both peptide-loaded and empty.
Formulation	Azide free phosphate buffered saline (PBS), approx. pH 7.4; 0.2 μm filter sterilized State: Low Endotoxin State: Liquid Ig fraction
Concentration	lot specific
Purification	Protein-A affinity chromatography (> 95% pure by SDS-PAGE)
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Background	HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system. It is expressed on antigen-presenting cells (dendritic cells, B lymphocytes, monocytes, macrophages).
Synonyms	HLA-DR, HLA class II histocompatibility antigen DR, MHC class II antigen DR
Reference Data

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