NMUR2 Mouse Monoclonal Antibody [Clone ID: 2A2]

Specifications

Product Data
Clone Name	2A2
Applications	IHC
Recommend Dilution	Immunohistochemistry on paraffin sections: 20 µg/ml (1/20). Positive control: Sceletal muscle.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	DNA vaccine
Specificity	This antibody detects  NMU-R2. The specificity of the antibody was verified by flow cytometry with cells expressing the recombinant protein.
Formulation	Phosphate buffered saline pH 7.2 (PBS) State: Purified State: Lyophilized affinity purified Ig fraction Stabilizer: 5 mg/ml bovine serum albumin (BSA) Preservative: 0.1% Kathon
Reconstitution Method	Reconstitute by adding 0.5 ml distilled water. This stock solution contains 0.4 mg/ml IgG.
Purification	Protein G
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	neuromedin U receptor 2
Database Link	Entrez Gene 56923 Human UniProt ID Q9GZQ4
Background	Neuromedin - U receptor 2 (NMU - R2) belongs to the G - protein coupled receptor 1 family. The mature protein is made up of 4 15 amino acids with one disulfide bond and three N - linked glycosylation sites. NMU - R2 is the receptor for Neuromedin s U (NMU) and S (NMS) which regulate important physiological functions, including feeding, energy balance, stress response, and nociception in the central nervous system (CNS). NMU - R2 is predominantly expressed in the CNS, particularly in the medulla oblongata, pontine reticular formation, spinal cord, and thalamus. Strong expression has also been described in testis whereas lower levels are present in a variety of peripheral tissues including the gastrointestinal tract, genitourinary tract, liver, pancreas, adrenal gland, thyroid gland, lung, spleen and thymus.
Synonyms	NMUR-2, NMU2R, TGR1, G-protein coupled receptor TGR-1
Reference Data

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