DDIT4L (2-98) Mouse Monoclonal Antibody [Clone ID: DDIT-03]

Specifications

Product Data
Clone Name	DDIT-03
Applications	FC, WB
Recommend Dilution	Flow cytometry (intracellular staining). Western blot.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	N-terminal recombinant fragment of human DDIT4L (amino acids 2-98)
Specificity	This antiobody recognizes DDIT4L / REDD2 protein, which belongs to stress-induced proteins involved in mediation of cell death.
Formulation	Phosphate buffered saline (PBS) State: Purified State: Liquid Ig fraction Preservative: 15 mM sodium azide, approx. pH 7.4
Concentration	lot specific
Purification	Protein-A affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	DNA damage inducible transcript 4 like
Database Link	Entrez Gene 115265 Human UniProt ID Q96D03
Background	DDIT4L (DNA-damage-inducible transcript 4-like), also known as REDD2 (regulated in development and DNA damage response 2) or RTP801L is a stress-inducted protein, which was shown to mediate monocyte cell death through a reduction in thioredoxin-1 expression, and is highly expressed in atherosclerotic lesions. Stimulation of DDIT4L expression in macrophages increases oxidized LDL-induced macrophage death.
Synonyms	DNA-damage-inducible transcript 4-like protein, HIF-1 responsive protein, REDD2, REDD-2, RTP801L
Reference Data

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