TWEAKR (TNFRSF12A) Mouse Monoclonal Antibody [Clone ID: ITEM-4]
CAT#: AM26769RP-N
TWEAKR (TNFRSF12A) mouse monoclonal antibody, clone ITEM-4, PE
Conjugation: Unconjugated
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CNY 4,340.00
货期*
5周
规格
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Specifications
Product Data | |
Clone Name | ITEM-4 |
Applications | FC |
Recommend Dilution | Flow cytometry. |
Reactivity | Human, Mouse |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Human CD266-transfected P815 cells |
Specificity | This antibody recognizes CD266 / TWEAK R, a TNFR superfamily receptor for CD255 / TWEAK, a TNF-like weak inducer of apoptosis. |
Formulation | Phosphate buffered saline (PBS) Label: PE State: Liquid purified Ig fraction Stabilizer: 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) Preservative: 15 mM sodium azide Label: Conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography. |
Conjugation | PE |
Storage Condition | Store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. |
Gene Name | tumor necrosis factor receptor superfamily member 12A |
Database Link | |
Background | CD266 / TWEAK R (TNFRSF12A), also known as FN14 (fibroblast growth factor-inducible 14) is a receptor for CD255 / TWEAK, the TNF-like weak inducer of apoptosis. CD266 is expressed on endothelial cells, as well as on some cancer tissues, and plays a role in CD255-induced endothelial cell migration, proliferation, and angiogenesis. The CD255-CD266 interaction, or antibody-mediated triggering of CD266 is also able to induce apoptosis and necrosis in CD266-positive cells (including tumor cells), which might have therapeutic potential. |
Synonyms | FGF-inducible 14, FN14, TNFRSF12A, Tweak receptor |
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