DR4 (TNFRSF10A) Mouse Monoclonal Antibody [Clone ID: B-N36]

Specifications

Product Data
Clone Name	B-N36
Applications	FN
Recommend Dilution	Functional Assay: Neutralizes TRAIL induced apoptosis on HEL cell line.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human TRAIL R1/Fc chimera
Specificity	This antibody recognises CD261, a 43-46 kDa protein.
Formulation	Phosphate-buffered saline. Sterile-filtered through 0.22 µm and treated to remove endotoxins. Carrier and preservative free State: Azide Free State: Liquid purified IgG fraction
Concentration	lot specific
Purification	Ion Exchange Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C.
Gene Name	tumor necrosis factor receptor superfamily member 10a
Database Link	Entrez Gene 8797 Human UniProt ID O00220
Synonyms	APO2, DR4, Death receptor 4, TRAIL receptor 1, TRAIL-R1, TNFRSF10A
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Apoptosis, Cytokine-cytokine receptor interaction, Natural killer cell mediated cytotoxicity

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