IL2 Mouse Monoclonal Antibody [Clone ID: B-G5]
CAT#: AM31260FC-N
IL2 mouse monoclonal antibody, clone B-G5, FITC
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CNY 3,872.00
货期*
5周
规格
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Specifications
Product Data | |
Clone Name | B-G5 |
Applications | FC |
Recommend Dilution | Flow Cytometry (Intra-cytoplasmic). |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Natural Human IL-2 |
Specificity | Recognizes both natural and recombinant Human Interleukin-2 (IL-2). |
Formulation | PBS containing 5% BSA as stabilizer and and 0.09% Sodium Azide as presrevative. Label: FITC State: Liquid purified IgG fraction. |
Purification | Ion Exchange Chromatography. |
Conjugation | FITC |
Storage Condition | Store the antibody undiluted at 2-8°C. DO NOT FREEZE! |
Gene Name | interleukin 2 |
Database Link | |
Background | Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells. |
Synonyms | IL-2, TCGF |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Allograft rejection, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Jak-STAT signaling pathway, T cell receptor signaling pathway, Type I diabetes mellitus |
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