Thrombomodulin (THBD) Mouse Monoclonal Antibody [Clone ID: B-A35]
CAT#: AM31356PU-N
Thrombomodulin (THBD) mouse monoclonal antibody, clone B-A35, Purified
Conjugation: FITC
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CNY 3,350.00
货期*
5周
规格
Specifications
Product Data | |
Clone Name | B-A35 |
Applications | FC |
Recommend Dilution | Flow Cytometry: Use 10 µl to label 10e6 cells or 100 µl of whole blood. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | TF1 cell line. |
Specificity | Recognises the soluble antigen. Recognises Thrombomodulin (TM), a 105 kDa protein. |
Formulation | PBS containing 1% BSA as stabilizer and 0.09% Sodium Azide as preservative State: Purified State: Liquid purified Ig fraction |
Purification | Ion Exchange Chromatography |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C. |
Gene Name | thrombomodulin |
Database Link | |
Background | CD141/Thrombomodulin is an exclusively endothelial cell surface glycoprotein that forms a 1:1 complex with thrombin. Binding of thrombin to this high-affinity receptor alters its specificity toward several substrates. The complex activates protein C approximately 1000 times faster than thrombin alone. Activated protein C degrades clotting factors V and VIII; thus, thrombomodulin converts thrombin into a physiologic anticoagulant. Thrombomodulin is also found in the circulatory and urinary systems, the physiologic significance of this is obscure. |
Synonyms | Thrombomodulin, THRM, Fetomodulin |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Complement and coagulation cascades |
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