BCL3 Hamster Monoclonal Antibody [Clone ID: Ham150-3.5]

CAT#: AM31856PU-N

BCL3 hamster monoclonal antibody, clone Ham150-3.5, Purified

Conjugation: Unconjugated Biotin FITC



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CNY 5,896.00


货期*
5周

规格
    • 250 ug

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Specifications

Product Data
Clone Name Ham150-3.5
Applications ELISA, FC, WB
Recommend Dilution This Clone has been described to work in ELISA, Western Blot and Flow Cytometry.
Reactivity Human, Mouse
Host Hamster
Clonality Monoclonal
Immunogen Recombinant Bcl-3-6-histidine tag from Armenian Hamster.
Fusion Partner: SP2/0 myeloma.
Specificity Recognizes B-cell Leukemia/lymphoma 3 (Bcl-3).
Formulation PBS containing 0.02% Sodium Azide as preservative
State: Purified
State: Liquid purified IgG fraction
Concentration lot specific
Purification Protein G Affinity Chromatography
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name B-cell CLL/lymphoma 3
Background B cell Lymphoma 3 is a member of the IkB subfamily of inhibitors. This subfamily is part of the NF-kB transcription factor protein family and it is suggested that a balance in the concentration of various NF-kB family members regulates apoptosis and survival of activated T cells.
Bcl-3 has been shown to have versatile functions such as cytoplasmic activation of p50 homodimers, translocation to the nucleus, and modulation of the transcriptional machinery in the nucleus. Bcl-3 activity often relies on several nuclear interacting proteins such as Tip60, Jab1, Bard1, and Pirin. The Mouse Bcl-3 coding region exhibits 80% homology with Human Bcl-3 which is associated with human B-cell chronic lymphocytic leukemias (CLLs).
Bcl-3 is detected in various tissues such as spleen and other lymphoid organs.
Synonyms BCL3, BCL4, D19S37
Reference Data
Protein Families Druggable Genome, Transcription Factors
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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