Klrd1 Rat Monoclonal Antibody [Clone ID: 15F.18D1]

Specifications

Product Data
Clone Name	15F.18D1
Applications	ELISA, FC, IF
Recommend Dilution	ELISA. Flow Cytometry. Tissue Distribution by Flow Cytometry Analysis: Mouse Strain: C57/BL6 Cell Concentration : 1x10e6 cells per test Antibody Concentration Used: 2.0 μg/10e6 cells Isotypic Control: FITC Rat IgG1
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Immunogen	Murine T cell clone AE7 cells Donor: Lewis Rat spleen cells Fusion Partner: Murine myeloma cell line SP2/0
Specificity	Anti-mouse CD94 monoclonal antibody detects the mouse CD94 receptor.
Formulation	PBS containing 0.02% sodium azide (NaN3) as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL. Label: FITC State: Liquid purified Ig fraction Label: Fluorescein isothiocyanate isomer 1
Concentration	lot specific
Conjugation	FITC
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	killer cell lectin-like receptor, subfamily D, member 1
Database Link	Entrez Gene 16643 Mouse UniProt ID O54707
Background	CD94 is a 180 amino acid, 70 KDa transmembrane glycoprotein that belongs to a family of murine Natural Killer (NK) cell receptors for MHC class I and is co-expressed as a heterodimer with NKG2 on the cellular surface. CD94 is expressed on NK cells as well as NK T cells. Both the murine CD94/NKG2 heterodimer and its human homologue are expressed on Th1 but not Th2 cells. Similar in function to the NKG2 family of receptors, CD94 is involved in NK target cell recognition, functions as an inhibitory receptor and plays an important role in adhesion and activation of the NK cell lineage. The unique expression of the CD94/NKG2 heterodimer on the Th1 subset of activated CD4+ cells suggests the potential use of our CL8950AP antibody in cell differentiation studies.
Synonyms	KLRD1, KP43, NK cell receptor
Reference Data

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