EMILIN2 Rat Monoclonal Antibody [Clone ID: 828B3B3]

Specifications

Product Data
Clone Name	828B3B3
Applications	FC, IP, WB
Recommend Dilution	Western Blot: Use at 1-5 µg/ml. IF/Immunohistochemistry on Frozen Sections. Immunoprecipitation. FACS Analysis.
Reactivity	Human
Host	Rat
Clonality	Monoclonal
Immunogen	Recombinant protein gC1q domain of EMILIN-2.
Specificity	This antibody was selected for its ability to detect Human Emilin-2.
Formulation	PBS State: Purified State: Lyophilized (0.2 μm filtered) purified IgG fraction
Reconstitution Method	Centrifuge vial prior to opening. Restore in sterile water to the final concentration of 0.1-1.0 mg/ml.
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month  or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	elastin microfibril interfacer 2
Database Link	Entrez Gene 84034 Human UniProt ID Q9BXX0
Background	Emilins (elastin microfibril interface located proteins) are extracellular matrix glycoproteins that localize to sites with proximity to elastin and microfibrils. They consist of an N-terminal cysteine-rich EMI domain and a conserved C-terminal gC1q-like domain. Emilin-1 is abundant in elastin-rich tissues such as blood vessels, skin, heart and lung. It influences placenta formation and initial organogenesis with a later role in interstitial connective tissue. Emilin-2 is larger than Emilin-1 and contains a unique proline-rich domain. It is likely involved in the process of elastogenesis. Multimerin-2 (also known as Emilin-3 or EndoGlyx-1) is expressed during embryonic development. Multimerin-1 (also known as Emilin-4) is expressed in platelets and the endothelium of blood vessels and may act as a carrier protein for platelet factor V. Emilin-5 is encoded by the Emilin-3 gene and is sometimes referred to as Emilin-3. It contains the N-terminal cysteine-rich EMI domain but lacks the C-terminal gC1q-like domain. Emilin-5 is expressed in human mesenchymal stem cells and plays an important role in skeletal development.
Synonyms	EMILIN-2, Protein FOAP-10
Reference Data

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