Integrin beta 1 (ITGB1) Mouse Monoclonal Antibody [Clone ID: DF7]

CAT#: AM32088PU-N

Integrin beta 1 (ITGB1) mouse monoclonal antibody, clone DF7, Ig Fraction



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CNY 8,892.00


货期*
5周

规格
    • 1 ml

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Specifications

Product Data
Clone Name DF7
Applications ELISA, IHC, WB
Recommend Dilution Western blotting: 1/1000.  
Immunohistochemistry.
Other Immunoassays for cellular and tumor biology.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Wheat germ agglutinin binding glycoproteins of Human fibroblasts.
Hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.
Specificity The antibody reacts with the b1 subunit of the integrin protein family. It reacts with an extracellular epitope of the beta-1 integrin molecule.
Formulation PBS
State: Ig Fraction
State: Liquid Ig fraction
Stabilizer: 1.0% BSA
Preservative: 0.09% Sodium Azide
Concentration lot specific
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C. 
Gene Name integrin subunit beta 1
Background CD29 or the integrin beta-1 belongs to the family of cell adhesion receptors. It was initially characterized independently as protein gpIIa appearing on platelets, as the common beta subunit of the very late activation antigen (VLA), and as a component of various protein complexes binding to extracellular matrix proteins. The CD29 is expressed at the cell surface exclusively as part of a heterodimer, in association with one of at least nine different integrin alpha subunits (alpha 1, alpha 2, alpha 3, alpha 4, alpha 5, alpha 6, alpha 7, alpha 8, and alpha v). With the exception of red blood cells and possible weak expression on granulocytes, CD29 is expressed nearly all cell and tissue types.
 Monoclonal antibodies against this β1-Integrin subunit are applicable in paraffin-embedded and frozen sections, immunoblotting and immunoprecipitation. Numerous studies have shown that β1 -Integrins have a distinct and wide cellular distribution and that there are alterations in malignant cells in their beta-1 integrin expression.
Synonyms Fibronectin receptor subunit beta, Integrin VLA-4 subunit beta, ITGB1, FNRB, MDF2, MSK12
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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