Scarb1 Mouse Monoclonal Antibody [Clone ID: 3D12]
CAT#: AM32107PU-N
Scarb1 mouse monoclonal antibody, clone 3D12, Liquid
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CNY 12,770.00
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Specifications
Product Data | |
Clone Name | 3D12 |
Applications | IHC, Neutralize |
Recommend Dilution | Western Blot. Flow Cytometry. Immunohistochemistry on Frozen Sections. Neutralization of biological activity: in vitro dilutions have to be made according to the amounts of SR-BI to be inactivated. Use 1/10 as starting working dilution. |
Reactivity | Rat |
Host | Mouse |
Clonality | Monoclonal |
Specificity | Monoclonal antibody 3D12 reacts with rat class B scavenger receptor type I (SR-BI). Clone 3D12 blocks the biological activity of rat SR-BI. For example, it inhibits the ability of SR-BI to mediate the corporation of lipids of HDL by SR-BI expressing cells. |
Formulation | PBS State: Liquid State: Liquid 0.2 µm filtered Stabilizer: 0.1% BSA Preservative: 0.02% Sodium Azide |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C. |
Gene Name | scavenger receptor class B, member 1 |
Database Link | |
Background | Scavenger receptors have been studied primarily for their ability to bind and internalize modified lipoproteins. They have been found in the development of atherosclerosis and other macrophage-associated functions. Scavenger receptors also function as pattern recognition receptors for a wide variety of pathogens. This finding indicates a potential role in host defense. SR-BI belongs together with CD36 to the class B scavenger receptor family. |
Synonyms | SRB1, SR-BI, CLA1, CLA-1, CD36L1 |
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