IL2 Receptor alpha (IL2RA) Mouse Monoclonal Antibody [Clone ID: CD25-3G10]

Specifications

Product Data
Clone Name	CD25-3G10
Recommend Dilution	Flow Cytometry: 5 μl is the maximum amount of reagent required for 1 x 10e6 cells.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Specificity	The antibody reacts with the α chain of the Interleukin-2 Receptor (55 kD glycoprotein). CD25 is expressed on activated T-lymphocytes and B-lymphocytes.
Formulation	Label: PE State: Liquid purified Ig fraction Preservative: 0,09% sodium azide Absorption emission: 488 nm / 575 nm
Conjugation	PE
Storage Condition	Store the antibody undiluted at 2-8°C. <b>DO NOT FREEZE!</b>
Gene Name	interleukin 2 receptor subunit alpha
Database Link	Entrez Gene 3559 Human UniProt ID P01589
Background	CD25 is the alpha chain of the IL-2 receptor. It is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes that associates with CD122 to form a heterodimer that can act as a high-affinity receptor for IL-2. CD25 is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemia's, neuroblastomas, and tumor infiltrating lymphocytes. Its soluble form, called sIL-2R may be elevated in these diseases and is occasionally used to track disease progression.
Synonyms	Interleukin-2 receptor alpha chain, IL-2 receptor alpha subunit, IL-2-RA, IL2-RA, p55, TAC antigen
Reference Data

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