CD62P (SELP) Mouse Monoclonal Antibody [Clone ID: CRC81]

Specifications

Product Data
Clone Name	CRC81
Recommend Dilution	Flow Cytometry: 1 μg is the maximum amount of reagent required for 1 x 10e6 cells. For studies on platelets care should be taken to avoid activation of platelets during drawing of blood. Platelet activation markers are weakly expressed on platelets prepared from directly fixed normal blood. The expression is max. on thrombin (1 U/ml) stimulated, washed platelets. Fix cells or platelets with 1% paraformaldehyde, wash and adjust to approx. 10e8/ml for further incubations.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human platelets
Specificity	The monoclonal antibody is directed against the CD62-antigen.
Formulation	Label: PE State: Liquid purified Ig fraction Stabilizer: 0,9% BSA Absorption emission: 488 nm / 575 nm
Conjugation	PE
Storage Condition	Store the antibody undiluted at 2-8°C. <b>DO NOT FREEZE!</b> This product is photosensitive and should be protected from light.
Gene Name	selectin P
Database Link	Entrez Gene 6403 Human UniProt ID P16109
Background	CD62, an integral membrane sialoglycoprotein 140 kD, also designated GMP-140 (granule membrane protein 140) or PADGEM, which is expressed in platelet alpha granules that are translocated to the platelet surface upon activation with strong agonists. A similar protein, present in endothelial cell Weibel-Palade bodies, is transiently expressed on the surface of activated endothelial cells and functions as adhesion molecule for granulocytes. The antibody does not interfere with the functional activity of CD62 as an adhesion receptor for neutrophils.
Synonyms	SELP, GMRP, GRMP, PADGEM, GMP-140, LECAM3
Reference Data

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