Prostate Specific Antigen (KLK3) Mouse Monoclonal Antibody [Clone ID: C3F12]

Specifications

Product Data
Clone Name	C3F12
Applications	Elispot, FC, IF, IHC, WB
Recommend Dilution	ELISPOT. Western blot. Flow Cytometry. Immunocytochemistry. Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections (10 μg/ml).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	PSA/Prostate Specific Antigen antibody was raised against prostate specific antigen (PSA)
Specificity	Recognizes Human PSA. Other species not tested.
Formulation	50mM Phosphate buffer pH 7.4, 0.1mM NaCl State: Purified State: Liquid purified IgG fraction Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Protein A Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	kallikrein related peptidase 3
Database Link	Entrez Gene 354 Human UniProt ID P07288
Background	Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a 33 kDa glycoprotein encoded in humans by the KLK3 gene. PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders.
Synonyms	Prostate-specific antigen, Semenogelase, Gamma-seminoprotein, P-30 antigen
Reference Data

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