GPR48 (LGR4) Rat Monoclonal Antibody [Clone ID: BBX-3A8]

CAT#: AM32985PU-N

GPR48 (LGR4) rat monoclonal antibody, clone BBX-3A8, Purified



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CNY 5,660.00


货期*
5周

规格
    • 100 ug

Product images

Specifications

Product Data
Clone Name BBX-3A8
Applications ELISA, FC, WB
Recommend Dilution Flow cytometry: 1.2 µg/106 cells.
Cell based ELISA with intakt, transiently transfected cells: 1/200-1/400.
Reactivity Human, Mouse
Host Rat
Clonality Monoclonal
Immunogen cDNA encoding Human LGR4.
Specificity Recognizes LGR4 / GPR48.
Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells.
Formulation PBS, pH 7.2
State: Purified
State: Liquid purified IgG fraction
Concentration lot specific
Purification Affinity Chromatography on Protein G
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name leucine-rich repeat containing G protein-coupled receptor 4
Background LGR4 (Leucine-rich repeat- containing G protein-coupled receptor 4) belongs to the superfamily of G protein-coupled receptors (GPCRs). It is a 951 amino acid multi-pass membrane protein and has multiple N-terminal leucine-rich repeats, which are important for interaction with the glycoprotein ligands, and 7 transmembrane domains (1,3). LGR4 is highly expressed in the adult human pancreas but also with moderate levels of expression in placenta, kidney, brain and heart (2). LGR4 functions as an orphan receptor that may be involved in physiologic activities throughout the cell. It is overexpressed in various cancer types and is thought to enhance carcinoma invasiveness and metastasis, suggesting an important role in tumor progression.
Synonyms G-protein coupled receptor 48
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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