CD94 (KLRD1) Mouse Monoclonal Antibody [Clone ID: B-D49]

Specifications

Product Data
Clone Name	B-D49
Applications	FC, IHC
Recommend Dilution	Flow Cytometry: Use 10 µl to label 106 cells or 100 µl of whole blood. Immunohistochemistry on Frozen Sections.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	IL-2 activated NK cells after tolerisation with activated PBL (CD56 negative).
Specificity	This antibody recognizes cell surface CD94.
Formulation	PBS State: Purified State: Liquid purified IgG fraction Stabilizer: 1% BSA Preservative: 0.09% Sodium Azide
Purification	Ion Exchange Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	killer cell lectin like receptor D1
Database Link	Entrez Gene 3824 Human UniProt ID Q13241
Background	Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
Synonyms	KLRD1, KP43, NK cell receptor
Reference Data

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