IL10 Mouse Monoclonal Antibody [Clone ID: 4H2]

Specifications

Product Data
Clone Name	4H2
Applications	ELISA, WB
Recommend Dilution	Indirect ELISA: The anti-Human IL-10 antibody clone 4H2 reacts with recombinant Human IL-10. Western blot: The anti-Human IL-10 antibody clone 4H2 reacts with recombinant Human IL-10 antigen (Immunogen) (Figure 1) and with Human IL-10 expressed in 293T cells (Figure 2).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant Human IL-10 (Insight genomics). Fusion Myeloma: F0
Specificity	This antibody reacts with Human IL-10. Other species not tested.
Formulation	Lyophilized from a solution in 0.01M PBS, pH 7.0 State: Aff - Purified State: Lyophilized purified IgG fraction
Reconstitution Method	Restore with doubled distilled water to a concentration of 1.0 mg/ml.
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	interleukin 10
Database Link	Entrez Gene 3586 Human UniProt ID P22301
Background	IL-10 is expressed by a variety of cells and plays an important role in inflammatory and immune responses. The biological activities of IL-10 include both immunosuppressive and immunostimulatory effects. It suppresses the production of pro-inflammatory cytokines by monocytes and neutrophils, and down-regulates the expression of activating and co-stimulatory molecules on monocytes and dendritic cells. It stimulates the growth of B cells and mast cells, and inhibits or enhances the activities of T cells depending on their activation conditions. Human IL-10 is a protein with 160 amino acids.
Synonyms	IL-10, CSIF, TGIF
Reference Data

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