ARMET (MANF) Mouse Monoclonal Antibody [Clone ID: 1G12]

Specifications

Product Data
Clone Name	1G12
Applications	ELISA, WB
Recommend Dilution	ELISA: 1/32000. Western Blot: 1/2000-1/4000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant Human MANF produced using CHO-based. Antigen is purified from cell culture supernatant.
Specificity	Recognizes Human MANF. Other species not tested.
Formulation	PBS pH 7.4 State: Aff - Purified State: Liquid purified IgG fraction Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Upon receipt, store (in aliquots) at -20°C to -80°C. Avoid repeated freezing and thawing.
Gene Name	mesencephalic astrocyte derived neurotrophic factor
Database Link	Entrez Gene 7873 Human UniProt ID P55145
Background	MANF is a trophic factor for midbrain dopamine neurons in vivo. It prevents the 6-OHDA- induced degeneration of dopamine neurons in rodent models of Parkinson’s disease (Lindholm et al., 2008, Voutilainen et al., 2009). When administered after 6-OHDA-lesioning it restores the dopaminergic function and prevents degeneration of dopamine neurons in substantia nigra pars compacta.
Synonyms	Arginine-rich protein, MANF
Reference Data

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