TNNI1 Mouse Monoclonal Antibody [Clone ID: AT36E7]

Specifications

Product Data
Clone Name	AT36E7
Applications	ELISA, WB
Recommend Dilution	The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1/500-1/5000. Recommended starting dilution is 1/5000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant Human TNNI1 (1-187aa) purified from E. coli
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein-A affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	troponin I1, slow skeletal type
Database Link	Entrez Gene 7135 Human UniProt ID P19237
Background	Troponin I, slow skeletal muscle, also known as TNNI1, belongs to the troponin I family. The troponin I subfamily contains three genes: TNNI-skeletal-fast-twitch, TNNI-skeletal-slow-twitch, and TNNI-cardiac. The TNNI-fast and TNNI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TNNI-cardiac gene is expressed exclusively in cardiac muscle tissue. TNNI1 is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation.
Synonyms	TNNI1
Reference Data

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