MICOS10-NBL1 Mouse Monoclonal Antibody [Clone ID: AT38G8]

CAT#: AM50052PU-N

MICOS10-NBL1 mouse monoclonal antibody, clone AT38G8, Purified



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CNY 6,620.00


货期*
5周

规格
    • 100 ul

Product images

Specifications

Product Data
Clone Name AT38G8
Applications ELISA, FC, IF, WB
Recommend Dilution ELISA.
Flow Cytometry.
Immunocytochemistry/Immunofluorescence.
Western blot / Immunoblot.
The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:1000.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Recombinant human NBL1 (18-181aa) purified from E. coli
Formulation PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
State: Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Protein-A affinity chromatography
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name MICOS10-NBL1 readthrough
Background NBL1 is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development and alternatively spliced transcript variants have been identified for this gene. Also, as a tumor suppressor gene of neuroblastoma may play an important role in preventing cells from entering the final stage (G1/S) of the transformation process. Read-through transcripts between this locus and the upstream mitochondrial inner membrane organizing system 1 have been observed.
Synonyms DAN, DAND1
Reference Data
Protein Families Secreted Protein
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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