MALT1 Mouse Monoclonal Antibody [Clone ID: SPM578]
CAT#: AM50100PU-S
MALT1 mouse monoclonal antibody, clone SPM578, Purified
Size: 20 ug
Need it in bulk or conjugated?
Get a free quote
CNY 5,606.00
货期*
5周
规格
Specifications
Product Data | |
Clone Name | SPM578 |
Applications | FC, IF, IHC, IP, WB |
Recommend Dilution | ELISA: Use Antibody without BSA for Coating. Flow Cytometry: 0.5-1 μg/106 cells. Immunofluorescence: 1-2 μg/ml. Western Blot: 0.5-1 μg/ml. Immunoprecipitation: 1-2 μg/500 μg protein lysate. Immunohistochemistry on Frozen and Formalin-Fixed Paraffin Sections: 0.5-1 μg/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes. Positive Control: Jurkat, Daudi or HeLa cells, or lymphoma. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Recombinant Human fragment of MALT1 protein (701-808). |
Specificity | Recognizes Human MALT1/Paracaspase. Other species not tested. Cellular Localization: Cytoplasmic. |
Formulation | 10mM PBS State: Purified State: Liquid purified IgG fraction from Bioreactor Concentrate Stabilizer: 0.05% BSA Preservative: 0.05% Sodium Azide |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C. |
Predicted Protein Size | 93 kDa |
Gene Name | MALT1 paracaspase |
Database Link | |
Background | MALT1/Paracaspase (MALT1) was independently identified as a member of the human paracaspase family and an interacting partner of B-cell lymphoma (Uren et al., 2000). MALT1 is a caspase-like protein that contains an N-terminal death domain, two Ig-like domains, and a C-terminal caspase-like domain. It binds to Bcl-10 through its Ig-like domains and cooperates with Bcl-10 to activate NF-kappaB. MALT1 is thought to play an important role in NF-kappaB signaling by enchancing NF-kappaB activation through interaction with Bcl-10 (Ho et al., 2005). Interaction between MALT1 and Bcl-10 mediates IKK activation in vitro through facilitatiing the ubiquitination of NEMO by the ubiquitinconjugating enzyme UBC13. |
Synonyms | Mucosa-associated lymphoid tissue lymphoma translocation protein 1, MLT, Paracaspase |
Reference Data |
Documents
Product Manuals |
FAQs |
SDS |
Resources
抗体相关资料 |
Customer
Reviews
Loading...