MelanA (MLANA) Mouse Monoclonal Antibody [Clone ID: SPM342]
CAT#: AM50108PU-S
MelanA (MLANA) mouse monoclonal antibody, clone SPM342, Purified
Size: 20 ug
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CNY 5,830.00
货期*
5周
规格
Specifications
Product Data | |
Clone Name | SPM342 |
Applications | FC, IF, IHC |
Recommend Dilution | Flow Cytometry: 0.5-1 μg/106 cells. Immunofluorescence: 1-2 μg/ml. Immunohistochemistry on Formalin-Fixed Paraffin Sections: 0.5-1 μg/ml for 30 minutes at RT. Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes: Positive Control: SK-MEL-13 and SK-MEL-19 Melanoma cell lines; Melanomas. |
Reactivity | Equine, Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Recombinant hMART-1 protein. |
Specificity | This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This Monoclonal Antibody labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. Cellular Localization: Cytoplasmic. Negative Species: Mouse and Rat. |
Formulation | 10mM PBS State: Purified State: Liquid purified IgG fraction from Bioreactor Concentrate Stabilizer: 0.05% BSA Preservative: 0.05% Sodium Azide |
Concentration | lot specific |
Purification | Protein A/G Chromatography |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C. |
Predicted Protein Size | 20-22 kDa (doublet) |
Gene Name | melan-A |
Database Link | |
Synonyms | Melan-A protein, MLANA, Antigen SK29-AA, LB39-AA, MelanA, MART1 |
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