CD11b (ITGAM) Rat Monoclonal Antibody [Clone ID: M1/70]
CAT#: AM50206PU-S
CD11b (ITGAM) rat monoclonal antibody, clone M1/70, Purified
Size: 20 ug
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AM50206PU-S is a replacement of TA320387.
CNY 5,606.00
货期*
5周
规格
Cited in 1 publication. |
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Specifications
Product Data | |
Clone Name | M1/70 |
Applications | IF, IHC, IP |
Recommend Dilution | ELISA: Use BSA free Antibody for coating. Flow Cytometry: 0.5-1 μg/million cells. Immunofluorescence: 0.5-1 μg/ml. Functional Studies: Use Antibody without BSA and Azide. Immunoprecipitation: 0.5-1 μg/500 μg protein lysate. Immunohistochemistry on Frozen Sections: 0.5-1.0 μg/ml for 30 minutes at RT. Positive Control: Monocytes & granulocytes, Lymph nodes and tonsils. |
Reactivity | Chimpanzee, Human, Mouse, Rabbit, Baboon |
Host | Rat |
Clonality | Monoclonal |
Immunogen | B10 Mouse spleen cells enriched for T lymphocytes. |
Specificity | CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin åM combines with the Integrin ∫2 to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin åM/∫2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Cellular Localization: Cell surface. |
Formulation | 10mM PBS State: Purified State: Liquid purified IgG fraction from Bioreactor Concentrate Stabilizer: 0.05% BSA Preservative: 0.05% Sodium Azide |
Concentration | lot specific |
Purification | Protein A/G Chromatography |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C. |
Predicted Protein Size | 95 kDa & 170 kDa |
Gene Name | integrin subunit alpha M |
Database Link | |
Synonyms | ITGAM, CR3A, CR-3 alpha chain, Integrin alpha-M, MAC1 |
Reference Data |
Citations (1)
The use of this Antibodies has been cited in the following citations: |
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Phagocytosis Is the Main CR3-Mediated Function Affected by the Lupus-Associated Variant of CD11b in Human Myeloid Cells
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PLoS ONE
,PubMed ID 23451151
[ITGAM]
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