CD11c (ITGAX) Mouse Monoclonal Antibody [Clone ID: HC1/1]

Specifications

Product Data
Clone Name	HC1/1
Applications	FC, IF, IHC, IP
Recommend Dilution	ELISA: Use BSA free Antibody for coating.  Functional Studies: Use Antibody without BSA and Azide. Flow Cytometry: 0.5-1 μg/million cells. Immunofluorescence: 0.5-1 μg/ml. Immunoprecipitation: 0.5-1 μg/500 μg protein lysate. Immunohistochemistry on Frozen Sections: 0.5-1.0 μg/ml for 30 minutes at RT. Positive Control: Human dendritic cells. Human lymph nodes and tonsils.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human monocytic U937 phorbol ester-treated cells.
Specificity	CD11c, also known as Integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst; expressed in hairy cell leukemias, acute non-lymphocytic leukemias, and some B-cell chronic lymphocytic leukemias. Cellular Localization: Cell surface.
Formulation	10mM PBS State: Purified State: Liquid purified IgG fraction from Bioreactor Concentrate Stabilizer: 0.05% BSA Preservative: 0.05% Sodium Azide
Concentration	lot specific
Purification	Protein A/G Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C.
Predicted Protein Size	145 kDa
Gene Name	integrin subunit alpha X
Database Link	Entrez Gene 3687 Human UniProt ID P20702
Synonyms	ITGAX, Integrin alpha-X, Leu M5
Reference Data

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