CD147 (BSG) Mouse Monoclonal Antibody [Clone ID: 8D6]
CAT#: AM50208PU-T
CD147 (BSG) mouse monoclonal antibody, clone 8D6, Purified
Size: 100 ug
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CNY 3,223.00
货期*
5周
规格
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Specifications
Product Data | |
Clone Name | 8D6 |
Applications | FC, IF, IHC, IP, WB |
Recommend Dilution | Functional Studies: Inhibits Homotypic Aggregation, Adhesion to Matrix Proteins, and Migation through Matrigel (Use Antibody without BSA/Azide). Flow Cytometry: 0.5-1 µg/million cells. Immunofluorescence: 1-2 µg/ml. Immunoprecipitation: 1-2 µg/500 µg protein. Western Blotting: 0.5-1 µg/ml. Immunohistochemistry on Frozen and Formalin-Fixed Paraffin Sections: 1-2 µg/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes. Positive Control: HSB2 cells, Colon or breast carcinoma. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Human T cell line Molt 13. |
Specificity | This Monoclonal Antibody recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis. Cellular Localization: Cell surface, cytoplasmic. |
Formulation | 10mM PBS State: Purified State: Liquid purified IgG fraction from Bioreactor Concentrate Stabilizer: 0.05% BSA Preservative: 0.05% Sodium Azide |
Concentration | lot specific |
Purification | Protein A/G Chromatography |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C. |
Predicted Protein Size | 35 kDa (non-reduced); 40 kDa (reduced) |
Gene Name | basigin (Ok blood group) |
Database Link | |
Synonyms | Basigin, BSG, EMMPRIN, TCSF |
Reference Data |
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