Von Willebrand Factor (VWF) Mouse Monoclonal Antibody [Clone ID: 3E2D10 + VWF635]
CAT#: AM50328PU-S
Von Willebrand Factor (VWF) mouse monoclonal antibody, clone 3E2D10 + VWF635, Purified
Size: 20 ug
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CNY 5,606.00
货期*
5周
规格
Specifications
Product Data | |
Clone Name | 3E2D10 + VWF635 |
Applications | FC, IF, IHC, IP, WB |
Recommend Dilution | ELISA: Use BSA free Antibody for coating. Flow Cytometry: 0.5-1 µg/million cells Immunofluorescence: 0.5-1 µg/ml. Western Blotting: 0.5-1 µg/ml. Immunoprecipitation: 0.5-1 µg/500 µg protein lysate. Immunohistochemistry on Frozen and Formalin-Fixed Paraffin Sections: 0.5-1 µg/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes. Positive Control: HUVEC cells or Tonsil |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Recombinant human vWF fragment (3E2D10 & VWF635). |
Specificity | This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi’s sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen. Cellular Localization: Cytoplasmic. |
Formulation | 10mM PBS State: Purified State: Liquid purified IgG fraction from Bioreactor Concentrate Stabilizer: 0.05% BSA Preservative: 0.05% Sodium Azide |
Concentration | lot specific |
Purification | Protein A/G Chromatography |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C. |
Predicted Protein Size | 250 kDa |
Gene Name | von Willebrand factor |
Database Link | |
Background | Von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. |
Synonyms | vWF, von Willebrand antigen 2, von Willebrand antigen II, F8VWF, Factor VIII Related Antigen |
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