PSME1 Mouse Monoclonal Antibody [Clone ID: AT12H3]

Specifications

Product Data
Clone Name	AT12H3
Applications	ELISA, WB
Recommend Dilution	The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human PSME1 (1-249aa) purified from E. coli.
Formulation	Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol. State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein-A affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	proteasome activator subunit 1
Database Link	Entrez Gene 5720 Human UniProt ID Q06323
Background	PSME1, also known as PA28 alpha, is an interferon gamma (IFNG) inducible proteasome activator required for presentation of certain major histocompatibility (MHC) class I antigens. The PSME1 complex is an altertive proteasome activator that does not employ the use of ubiquitin. The PSME1 complex is composed of two homologous subunits, alpha and beta, which have similar catalytic properties and associate to form a hexameric ring.
Synonyms	PSME-1, IFI5111, Proteasome activator complex subunit 1, Proteasome activator 28 subunit alpha, PA28alpha, PA28a, 11S regulator complex subunit alpha, REG-alpha, IGUP I-5111
Reference Data
Protein Pathways	Antigen processing and presentation, Proteasome

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