Streptococcus pneumoniae Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IF
Recommend Dilution	ELISA. IFA. It is also suitable for Conjugation purposes.
Reactivity	Streptococcus pneumoniae
Host	Rabbit
Clonality	Polyclonal
Immunogen	Whole cell blend of multiple serotypes.
Specificity	This antibody recognizes types 3, 4, 6, 7, 9, 14, 18, 19 and 23 surface antigens of S. pneumonia. Antiserum is not absorbed and may react with related microorganisms.
Formulation	0.01M PBS, pH 7.2 containing 0,09% Sodium Azide as preservative without stabilizing proteins State: Purified State: Liquid purified Ig fraction (> 95% pure)
Concentration	lot specific
Purification	Protein A Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Background	Streptococcus pneumoniae are Gram positive diplococci , alpha hemolytic aerotolerant anaerobes. S. pneumoniae is a significant human pathogen, being recognized as a major cause of pneumonia in the late 19th century, and is currently the subject of many humoral immunity studies. S. pneumoniae is a transient member of the normal flora, colonizing the nasopharynx of 40% of healthy adults and children with no adverse effects. There are more than 90 serotypes: serotypes 6, 14, 18, 19, and 23 are the most prevalent accounting for 60-80% of infections depending on the area of the world. Pneumococcal infection accounts for more deaths than any other vaccine preventable bacterial disease. S. pneumoniae can express several different virulence factors which contribute to some of the clinical manifestations seen during infection.
Reference Data

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