MIA2 Rabbit Polyclonal Antibody
CAT#: AP01153BT-N
MIA2 rabbit polyclonal antibody, Biotin
Size: 25 ug
Conjugation: Unconjugated
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CNY 4,790.00
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Specifications
Product Data | |
Applications | ELISA, WB |
Recommend Dilution | ELISA: Direct: To detect hMIA-2 (using 100 μl/well antibody solution) a concentration of 0.25 - 1.0 μg/ml of this antibody is required. In conjunction with compatible secondary reagents, it allows the detection of at least 0.2 - 0.4 ng/well of recombinant hMIA-2. Sandwich: To detect hMIA-2 (using 100 μl/well antibody solution) a concentration of 0.25 - 1.0 μg/ml of this antibody is required. In conjunction with Polyclonal Anti-Human MIA-2 as a capture antibody, it allows the detection of at least 0.2 - 0.4 ng/well of recombinant hMIA-2. Western blot: To detect hMIA-2 this antibody can be used at a concentration of 0.1 - 0.2 μg/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant hMIA-2 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions. |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Highly pure (> 98 %) recombinant human MIA-2 |
Specificity | This antibody detects MIA-2. |
Formulation | PBS, pH 7.2 Label: Biotin State: Sterile filtered lyophilized Ig fraction |
Reconstitution Method | Centrifuge vial prior to opening. Restore in sterile PBS containing 0.1 % BSA to a concentration of 0.1 -1 .0 mg/ml. |
Purification | Affinity chromatography |
Conjugation | Biotin |
Storage Condition | Store the lyophilized antibody at -20 °C. Following reconstitution it is stable for two weeks at 2 - 8 °C. Frozen aliquots are stable for 6 months when stored at -20 °C. Avoid repeated freezing and thawing. |
Gene Name | CTAGE family member 5 |
Database Link | |
Background | MIA2 (Melanoma inhibitory activity 2) is a secreted cytokine and a member of the MIA/OTOR family. It is predominantly expressed in hepatocytes and may play a role in the pathophysiology of liver disease. Elevated levels of MIA2 may represent a clinically useful marker for diagnosis of hepatic disease activity and severity. MIA2 may act as a tumor suppressor in hepatocellular carcinoma. |
Synonyms | Melanoma inhibitory activity protein 2 |
Reference Data |
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