Neurokinin A Receptor (TACR2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	Western Blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to amino acids 320-370 of Human NK-2R.
Specificity	This antibody detects endogenous levels of NK-2R protein. (region surrounding Pro340)
Formulation	Phosphate buffered saline (PBS), pH~7.2 State: Aff - Purified State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE). Preservative: 0.05% Sodium Azide
Concentration	1.0 mg/ml
Purification	Affinity Chromatography using epitope-specific immunogen.
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	~ 44 kDa
Gene Name	tachykinin receptor 2
Database Link	Entrez Gene 6865 Human UniProt ID P21452
Background	This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neuropeptide substance K, also referred to as neurokinin A. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. It has been reported to be expressed in trachea, lung, and gastrointestinal tract. ESTs have been isolated from human heart/melanocyte/uterus, prostate, and uterus libraries.
Synonyms	Substance-K receptor, NKNAR, TAC2R, NK-2 receptor, NK-2R, Neurokinin A receptor, Tachykinin receptor 2
Reference Data

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