MRG15 (MORF4L1) Rabbit Polyclonal Antibody
CAT#: AP01243PU-N
MRG15 (MORF4L1) rabbit polyclonal antibody, Aff - Purified
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CNY 4,640.00
货期*
2周
规格
Specifications
Product Data | |
Applications | IF, IHC, WB |
Recommend Dilution | Western Blot: 1/500-1/1000. Immunofluoresecnce: 1/50-1/200. Immunohistochemistry on paraffin sections: 1/50-1/200. |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide, corresponding to amino acids 23-75 of Human MRG15. |
Specificity | This antibody detects endogenous levels of MRG15 protein. (region surrounding Arg56) |
Formulation | Phosphate buffered saline (PBS), pH~7.2 State: Aff - Purified State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE) Preservative: 0.05%Sodium Azide |
Concentration | 1.0 mg/ml |
Purification | Affinity Chromatography using epitope-specific immunogen. |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Predicted Protein Size | ~ 41 kDa |
Gene Name | mortality factor 4 like 1 |
Database Link | |
Background | MRG15 ia a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis and DNA repair. |
Synonyms | MORF4L1, MRG15, FWP006, HSPC008, HSPC061, PP368, Mortality factor 4-like protein 1, MSL3-1 protein |
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