TGF beta Receptor I (TGFBR1) Rabbit Polyclonal Antibody

CAT#: AP01457PU-S

TGF beta Receptor I (TGFBR1) rabbit polyclonal antibody, Aff - Purified

Size: 100 ug 25 ul



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CNY 800.00


货期*
2周

规格
    • 25 ul

Product images

Specifications

Product Data
Applications WB
Recommend Dilution Western Blot: 1/500-1/1000.
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide, corresponding to amino acids 150-200 of Human TGFβ RI.
Specificity This antibody detects endogenous levels of TGFβ RI protein (region surrounding Glu161).
Formulation Phosphate buffered saline (PBS), pH~7.2
State: Aff - Purified
State: Liquid purified Ig fraction (> 95% by SDS-PAGE)
Preservative: 15 mM Sodium Azide
Concentration 1.0 mg/ml
Purification Affinity Chromatography using epitope-specific immunogen
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Predicted Protein Size ~ 55 kDa
Gene Name transforming growth factor beta receptor 1
Background Three members of the TGF beta family, TGF beta 1, TGF beta 2 and TGF beta 3, are known in mammals. TGF betas mediate their activity by high affinity binding to the type 2 receptor, which requires both its kinase activity and association with members of a series of related type 1 receptors called activin receptor like kinase (ALK) 1 to 6. Of these, only ALK5 has been shown to represent a functional TGF beta type 1 receptor, but only ALK2 and ALK4 bind activin with high affinity. TGF beta R3 binds TGF beta and retains TGF beta for presentation to the signaling receptors.
Synonyms TGF-beta receptor type-1, TGF-beta type I receptor, TbetaR-I, TGFR-1, ALK5, SKR4
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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