KCNK1 Rabbit Polyclonal Antibody
CAT#: AP01494PU-N
KCNK1 rabbit polyclonal antibody, Aff - Purified
Size: 25 ul
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CNY 1,999.00
CNY 4,640.00
货期*
2周
规格
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | Western Blot: 1/500-1/1000. |
Reactivity | Human, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Specificity | This antibody detects endogenous levels of TWIK-1 protein. (region surrounding Val322) |
Formulation | Phosphate buffered saline (PBS), pH~7.2 with 0.05% Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE) |
Concentration | 1.0 mg/ml |
Purification | Affinity Chromatography using epitope-specific immunogen |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Predicted Protein Size | ~38 kDa |
Gene Name | potassium two pore domain channel subfamily K member 1 |
Database Link | |
Background | K+ channels are divided into three subclasses, reflecting the number of transmembrane segments (TMS), which are designated 6TMS, 4TMS and 2TMS. Members of the 4TMS class contain two distinct pore regions, and include TASK, TREK, TRAAK and TWIK. TWIK-1 mRNA is expressed abundantly in brain and at lower levels in lung, kidney and skeletal muscle. The molecular weight of TWIK-1 in mouse brain is 40 kDa under reducing conditions. TWIK-2 shares low sequence homology with other mammalian family group members, and only 34% homology with TWIK-1. Human TWIK-2 is expressed in pancreas, placenta and heart, while mouse TWIK-2 is expressed in liver. TWIK-2 is inhibited by intracellular, but not extracellular, acidification. |
Synonyms | KCNK1, HOHO1, KCNO1, TWIK1, Potassium channel subfamily K member 1, Potassium channel KCNO1 |
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