CDK1 pThr161 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Western Blot: 1/500-1/1000. Immunohistochemistry on paraffin sections: 1/50-1/200.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Specificity	p-CDC2 (pTht161) antibody detects endogenous levels of p-CDC2 protein.
Formulation	Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. State: Aff - Purified State: Liquid purified Ig fraction
Concentration	1.0 mg/ml
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	~ 34 kDa
Gene Name	cyclin-dependent kinase 1
Database Link	Entrez Gene 983 Human UniProt ID P06493
Background	The cell cycle in Arabidopsis thaliana mediates organ morphogenesis, cell proliferation and differentiation, and these functions are restricted to the eristems. The cell cycle is controlled by cyclin-dependent kinases, which bind to positive regulators called cyclins. In particular, Arabidopsis B-type cyclin controls cell cycle progression by regulating gene expression late in the G2 and M phases. Expression of cyclin Ds have been shown to increase in response to sucrose. Cdc2 and Cdc2B control cell cycle progression after forming a complex with cyclin. Prolifera and pelota are required for DNA replication and meiotic cell division, respectively.
Synonyms	CDK1, CDC2, CDC28A, CDKN1, P34CDC2, p34 protein kinase
Reference Data

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